5-lipoxygenase (5-LOX) is a member of the lipoxygenase family of enzymes. It transforms fatty acids into

leukotrienes. Excess levels of the enzyme 5-LOX sets in motion inflammatory responses that have been

linked to common effects in aging individuals. Normal aging results in higher-than-desired levels of 5-LOX.

The typical American diet adds to the danger. Foods rich in omega-6 fatty acids like red meat, poultry,

eggs and dairy products, along with high-glycemic carbohydrates, trigger overproduction of arachidonic

acid. In response to high levels of arachidonic acid, the body produces the 5-LOX enzyme. 5-LOX

breaks down arachidonic acid to pro-inflammatory compounds like leukotriene B4,6 a molecule

that mediates attacks to joints, arterial walls, and other tissues. 5-LOX itself

facilitates undesirable cell division changes.